LTQ Orbitrap Hybrid Mass Spectrometer

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LTQ Orbitrap XL ETD™

LTQ Orbitrap Hybrid Mass Spectrometer

The Comprehensive Proteomics Solution for Protein ID, Characterization and Quantitation

Combining patented Orbitrap technology with the highly successful LTQ™ linear ion trap, Thermo Scientific's LTQ Orbitrap™ enables faster, more sensitive and more reliable detection and identification of compounds in complex mixtures. Its outstanding mass accuracy, mass resolution and reliable high sensitivity MSⁿ performance make it a clear alternative to existing hybrid Time-of-Flight systems.

ETD Upgrades are available for LTQ Orbitrap and LTQ Orbitrap XL.

The Thermo Scientific LTQ Orbitrap XL ETD is the most powerful instrument for proteomics analyses: It combines three different and complementary fragmentation techniques CID, HCD, and ETD with the proven benefits of Orbitrap™ technology. It is the most comprehensive solution for complex PTM analysis, intelligent sequencing of peptides, top-down and middle-down analysis, and protein quantitation via stable isotope labelling such as iTRAQ™ or label-free quantitation.

The LTQ Orbitrap XL ETD offers:

High resolution and accurate mass for complex ETD spectra analysis
Data Dependent Decision Tree for intelligent peptide sequencing
Multiple activation modes for unambiguous sequence assignments
Accurate mass for the most confident analysis of PTMs

Thermo Scientific offers the LTQ Orbitrap™ hybrid mass spectrometer with superior performance for small molecule research, drug discovery, proteomics, metabolite identification, and metabolomics. The LTQ Orbitrap represents the first totally new mass analyzer to be introduced to the market in over 20 years.

Achieve unequivocal analytical performance

Robust Accurate Mass Capabilities:
• Intensity independent mass accuracy
• No internal calibration required
• Ease of use for the productive laboratory

Unsurpassed LC/MSⁿ Performance:
• Sub-femtomole sensitivity
• Rapid acquisition rates
• Multiple ionization modes, inlets and chromatographic solutions

Confident Metabolite Identification:
• Outstanding MSⁿ spectral quality and accurate mass information
• Data Dependent™ acquisition with Dynamic Exclusion™
• Routine high resolution, high quality MSⁿ analysis for structural elucidation
• Wide dynamic range and high sensitivity for confident component identification in complex matrices

Breakthrough Electrostatic Ion Trap Technology

New Orbitrap Technology Offers:
• Highest ion trapping efficiencies
• Large ion capacity
• Stable and robust operation
• Patented analyzer technologies

Orbitrap Models Offered by Thermo Scientific

LTQ Orbitrap Discovery
LTQ Orbitrap XL
LTQ Orbitrap XL ETD™
MALDI LTQ Orbitrap™

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