FOR IMMEDIATE RELEASE
Chromatography and Mass Spectrometry
Media Contact Information: Secondary Contact Information:
Name: Laura Browne/Charlotte Culley Stephanie Kubina
Phone: +44 1477 539539 +1 (408) 965-6022
Email: thermo@scottpr.com
stephanie.kubina@thermofisher.com
Website: www.scottpr.com
Thermo Fisher Scientific Partners with Phytronix
Technologies to Offer Ultra High-Speed LDTD Technology for Large
Volume LC/MS Analyses
SAN JOSE, California, (November 12, 2007) – Thermo Fisher Scientific
Inc., the world leader in serving science, announces a strategic
partnership with Phytronix Technologies, a Canada-based company, for
the use of Laser Diode Thermal Desorption (LDTD) technology. LDTD™
technology enhances the existing Thermo Scientific TSQ Quantum™
LC/MS product portfolio by offering ultra fast sample analysis for
both quantitative and qualitative applications in high-throughput
drug discovery, drug development, food safety and environmental
applications.
This unique technology, consisting of a semi-conductor based laser
diode, allows scientists to rapidly analyze compounds. The workflow
is enhanced by simply loading the Phytronix Lazwell™ 96-well plate
with the sample, and inserting the plate into the LDTD ion source
operating at atmospheric pressure. The LDTD technology increases the
speed of analysis of compounds by 20 to 100 times compared to
established techniques based on liquid chromatography with mass
spectrometry. Pharmacokinetic studies using LDTD technology can be
performed in less than 10 minutes, and enzyme inhibition assays in
18 minutes – compared to 10 hours presently required with LC-MS
techniques.
The LDTD™ ion source utilizes an infrared laser diode to thermally
desorb the dried sample. The desorbed sample is transferred in the
APCI region where it is ionized and then transferred into the MS.
When configured with the TSQ Quantum, the system delivers fast and
efficient quantitative and qualitative results. Applications include
the analysis of sulfonamide residues in milk, analysis of explosives
such as HMX, RDX, and TNT, and analysis of fatty acids in both
positive and negative ion mode. One unique advantage of this
technology is that it can be used in mobile units for real-time,
on-location environmental testing as seen in the operation of an
LDTD-based TSQ Quantum for air quality testing by the Québec
Environmental Agency.
See Thermo Scientific LC/MC solutions for drug discovery and
development at the American Association of Pharmaceutical Scientists
(AAPS) meeting in San Diego November 12-14, 2007, Booth # 709. See
Phytronix Technologies for high-throughput solutions at AAPS, Booth
#2045. See www.thermo.com/aaps for links to show schedule and
details.
For more information on LDTD technology, see www.phytronix.com. For
more about Thermo Scientific liquid chromatography and mass
spectrometry product lines, please call +1 800-532-4752, e-mail
analyze@thermofisher.com or visit www.thermo.com/ms.
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Thermo Scientific is part of Thermo Fisher Scientific, the world
leader in serving science.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in
serving science, enabling our customers to make the world healthier,
cleaner and safer. With an annual revenue rate of more than $9
billion, we employ 30,000 people and serve over 350,000 customers
within pharmaceutical and biotech companies, hospitals and clinical
diagnostic labs, universities, research institutions and government
agencies, as well as environmental and industrial process control
settings. Serving customers through two premier brands, Thermo
Scientific and Fisher Scientific, we help solve analytical
challenges from routine testing to complex research and discovery.
Thermo Scientific offers customers a complete range of high-end
analytical instruments as well as laboratory equipment, software,
services, consumables and reagents to enable integrated laboratory
workflow solutions. Fisher Scientific provides a complete portfolio
of laboratory equipment, chemicals, supplies and services used in
healthcare, scientific research, safety and education. Together, we
offer the most convenient purchasing options to customers and
continuously advance our technologies to accelerate the pace of
scientific discovery, enhance value for customers and fuel growth
for shareholders and employees alike. Visit www.thermofisher.com.
For further press information please contact: Laura Browne, The
Scott Partnership, 1 Whiteside, Station Road, Holmes Chapel,
Cheshire. CW4 8AA United Kingdom Tel: + 44 1477 539539 Fax: +44 1606
1477 539540 E-mail: thermo@scottpr.com
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