September 20th, 2007

FOR IMMEDIATE RELEASE


GeneBio and the SIB Launch an Extended Version of Aldente, SIBs Peptide
Mass Fingerprint Tool


Geneva, Switzerland September 19, 2007 - Geneva Bioinformatics (GeneBio)
SA and the Swiss Institute of Bioinformatics (SIB) today announced the
release of an enhanced version of Aldente, the peptide mass fingerprint
(PMF) tool developed by the SIBs Proteome Informatics Group. This extended
commercial version available from GeneBio builds upon the existing free
version of Aldente accessible from the SIBs ExPASy server and heavily used
by the scientific community since 2002. Aldente is another in a long list of
cooperative efforts between the two organizations.



One of the strengths of Aldente is to include a mass spectral realignment
method in the scoring process. The so called Hough transform as implemented
in Aldente is very robust and performs equally well with crowded or poor
spectra, allowing also the validation of the presence of a simple mixture of
proteins in a spectrum. Last but not least, the close neighbourhood of and
synergies with the Swiss-Prot group enable Aldente to automatically search
for post-translationally modified peptides as annotated in Swiss-Prot.
GeneBios extended version allows Aldente users, amongst others, to:

- Use the software locally, thus uploading their proprietary
sequence databases in a completely secured environment,

- Perform batch submission,

- Access their job history together with the possibility to
re-submit those jobs,

- Access results and graphically evaluate them in various levels of
detail as well as export them in different formats.



Aldente is a great addition to GeneBios existing protein identification and
characterization activities, allowing those to span from PMF analysis
through Aldente to MS/MS analysis using Phenyx (www.phenyx-ms.com). In the
near future this enhanced version of Aldente will work seamlessly with
Phenyx allowing users to visualize both MS/MS and PMF results through the
same user interface; the combination of the two platforms provides users
with a powerful set of tools that meet the needs of life science workers
using proteomics software.



We are extremely pleased to once again work with GeneBio in order to bring
one of our widely used developments, Aldente this time, to the market, said
Ron D. Appel, Head of the Proteome Informatics Group and SIB cofounder.
Aldente is already a powerful tool. Making it available in an enhanced
version through GeneBio and aligning it with GeneBios Phenyx gives
researchers access to an integrated platform that can only benefit ongoing
life science research.



The addition of Aldente to the GeneBio product lineup brings both an
exceptional platform and enhanced functionality to our users, said Nasri
Nahas, CEO of GeneBio. Not only can it stand on its own as an excellent
tool, but it also meshes perfectly with our Phenyx offering in order to
bring users a tier-one protein identification platform that covers both
MS/MS and PMF search functionalities. This is yet another example of the
benefits inherent in mixing the commercial and academic worlds to better
fulfill market expectations.



For more information concerning Aldente, please go to
www.genebio.com/aldente.



GeneBio will be present at HUPO 2007 in Seoul, Korea from October 6 10 at
booth #C9-2. Please stop by to receive an Aldente demo or answers to your
questions about the platform, as well as more information about other
products.





About GeneBio
Geneva Bioinformatics (GeneBio) SA is a leading bioinformatics company
providing the life science community with world-class proteomics software
that bridges the gap between information gathering and knowledge generation.
Established in 1997, we focus our expertise on protein identification and
characterization as well as proteome imaging, offering clients and partners
a high degree of specialization essential to proteomics research. Close ties
to academic peers and a thorough network of distribution and strategic
partners give us both unfettered access to scientific excellence and
recognized market presence so that we may best serve the scientific
community. For more information about GeneBio, please visit:
www.genebio.com.





About the Swiss Institute of Bioinformatics (SIB)
The SIB is an academic not-for-profit foundation established on March 30,
1998 whose mission is to promote research, the development of databases and
software, teaching and service activities in the field of bioinformatics, in
Switzerland and abroad. For more information about the SIB, please visit:
www.isb-sib.ch.



The Proteome Informatics Group (PIG) is part of the SIB and focuses its
activities on research and services in proteome informatics, in particular
the development of software tools and databases for proteomics. Some of
these activities have been ongoing since 1984. The PIG has also created
ExPASy (www.expasy.org), the worlds first Web site for life sciences.







GeneBio contact:

Andrew Smith

andrew.smith@genebio.com

Tel. +41.22.702.99.00





SIB contact:

Patricia Palagi

patricia.palagi@isb-sib.ch

Tel. +41.22.379.50.50





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